University Veterinary Hospital, University College Dublin, Bellfield Campus, Dublin 4, Ireland.
Res Vet Sci. 2012 Aug;93(1):143-9. doi: 10.1016/j.rvsc.2011.06.024. Epub 2011 Jul 19.
Bovine Herpes Virus 1 (BoHV-1) is an important viral disease of cattle worldwide. In endemically infected herds, there is an incomplete understanding of the epidemiology of BoHV-1 infection. We describe the dynamics of animal-level BoHV-1 antibody status on 9 endemically infected commercial dairy herds, based on the results of serial milk antibody testing. Results were used to identify primary exposure, secondary exposure (from re-activation or re-exposure) and development of test-negative latent carrier (TNLC) status. 4153 test results from 828 cow-lactations were analysed. Primary exposure occurred on two herds, secondary exposure occurred on all herds and development of TNLC status occurred in eight herds. Incidence of secondary exposure reduced over time and may have been related to increasing time since parturition. Regular secondary exposure is required to maintain measurable antibody status.
牛疱疹病毒 1 型（BoHV-1）是一种在全球范围内对牛具有重要影响的病毒性疾病。在地方性感染牛群中，对 BoHV-1 感染的流行病学还不完全了解。我们基于连续的牛奶抗体检测结果，描述了 9 个地方性感染的商业奶牛场的动物水平 BoHV-1 抗体状态的动态变化。结果用于确定初次感染、二次感染（来自再激活或再接触）和检测阴性潜伏携带者（TNLC）状态的发展。对 828 次奶牛泌乳的 4153 次检测结果进行了分析。两个牛场发生了初次感染，所有牛场均发生了二次感染，8 个牛场发展为 TNLC 状态。二次感染的发生率随着时间的推移而降低，这可能与产犊后时间的增加有关。定期的二次感染是维持可测量的抗体状态所必需的。
