Eberhardt H J, Friedrich S, Herrmann T, Roy U
Abteilung für Strahlentherapie, Medizinische Akademie Carl Gustav Carus, Dresden.
Radiobiol Radiother (Berl). 1990;31(5):415-8.
Malignant neoplasias in childhood generally are an increased risk for the patient to fall ill with a second tumor. Second tumors in former irradiation field are seldom, but are acknowledged radiogenically if histology is different to that of the first tumor and a sufficiently long period is between the two tumors. A patient is represented who had been operated and irradiated because of an adenosarcoma of the kidney at the age of seven and who has fallen ill with a neurogenic sarcoma in irradiation area more than 30 years later. The same patient had to suffer from radiogenic retardation during differentiation of lumbar apparatus of attitude and locomotion and on the other hand he became father of a healthy daughter at the age of 32.
儿童期恶性肿瘤通常会增加患者患第二种肿瘤的风险。既往照射区域出现的第二种肿瘤很少见,但如果组织学与第一种肿瘤不同且两种肿瘤之间间隔足够长的时间,则被认为是放射性诱发的。本文介绍了一名患者,他七岁时因肾腺肉瘤接受了手术和放疗,30多年后在照射区域患了神经源性肉瘤。该患者在腰椎姿势和运动分化过程中出现了放射性发育迟缓,另一方面,他在32岁时成为了一个健康女儿的父亲。