毒扁豆碱对大鼠血浆血管紧张素转换酶活性的影响。
Effect of physostigmine on plasma angiotensin converting enzyme activity in rat.
作者信息
Verma P S, Taylor R E
机构信息
Department of Pharmacology, Howard University, Washington, D.C. 20059.
出版信息
Res Commun Chem Pathol Pharmacol. 1990 Nov;70(2):245-8.
PMID:2177564
Abstract
The effect of physostigmine on plasma angiotensin converting enzyme activity in rat was studied. Following administration of the drug (0.3 mg/kg), plasma angiotensin activity fell significantly at 45 min (P less than 0.05) and continued to decline during the course of the experiment. These data demonstrate that physostigmine inhibits plasma angiotensin converting enzyme activity in rat.
摘要
研究了毒扁豆碱对大鼠血浆血管紧张素转换酶活性的影响。给予该药物（0.3毫克/千克）后，血浆血管紧张素活性在45分钟时显著下降（P小于0.05），并在实验过程中持续下降。这些数据表明毒扁豆碱可抑制大鼠血浆血管紧张素转换酶活性。
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