Department of Psychiatry, National institute of Mental Health and Neurosciences, Bangalore.
Indian J Psychiatry. 1992 Apr;34(2):124-7.
Thirty melancholic patients participated in a double blind trial comparing efficacy of modified bilateral sinewave ECT given twice or thrice weekly. Seizure was monitored on a single channel EEG tracing. All patients received ECTs in the first two weeks of the four week study period. Seizure duration estimate from EEG tracings available for 22 patients (10 patients of thrice weekly group) on all occasions of first two weeks were analysed. Seizure durations significantly reduced through the course in both the groups. Twice weekly ECTs led to significantly less decrements in the seizure duration. This differential reduction was not related to the therapeutic outcome. The improvement in depression in both groups of patients was comparable at the end of two weeks.
30 名忧郁症患者参与了一项双盲试验,比较每周两次或三次给予改良双边正弦波电惊厥治疗的疗效。通过单通道 EEG 描记监测癫痫发作。所有患者在为期四周的研究期的前两周内接受 ECT。对所有前两周的 22 名患者(每周 3 次组的 10 名患者)的 EEG 描记可获得的癫痫持续时间进行了分析。在两组中,癫痫发作持续时间均随时间显著减少。每周两次的 ECT 可显著减少癫痫发作持续时间的减少。这种差异减少与治疗效果无关。两组患者在两周结束时的抑郁改善情况相当。