Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.
Med Phys. 2011 May;38(5):2353-8. doi: 10.1118/1.3574871.
Phase-contrast (PC) edge enhancement occurs at the boundary between different tissues and is an interference effect that results from the differential phase-shifts that the x-rays acquire while traversing the two tissues. While observable in planar phase-contrast radiographs, the impact of digital tomosynthesis on this edge enhancement effect has not been previously reported. The purpose of this work is to demonstrate: (1) that phase-contrast digital tomosynthesis (PC-DTS) is possible with a conventional x-ray source, (2) that the reconstructed tomosynthesis images demonstrate and retain edge enhancement as compared to planar phase-contrast radiographs and (3) tomosynthesis improves object contrast by reducing the effects of superimposed structures.
An unmodified, commercially available cabinet x-ray system (Faxitron LX-60) was used. The system contains a tungsten anode x-ray tube that was operated at 24 kVp and 3 mAs for each PC radiographic image taken, with a nominal focal spot size of 0.010 mm. The digital detector uses CsI/CMOS with a pixel size of 0.054 mm x 0.054 mm. Objects to be imaged were attached to a computer-controlled rotating motor and are rotated +/- 25 degrees about a central position in one degree increments. At each increment, three phase-contrast radiographs are taken and then averaged to reduce the effect of noise. These planar images are then used to reconstruct a series of 56 longitudinal tomographic images with an image offset increment of about 0.7 mm.
Tomographic z-plane resolution was measured to be approximately 4 mm. When compared to planar PC images, the tomosynthesis images were shown to retain the PC boundary edge enhancement in addition to an improvement in object contrast.
Our work demonstrates that PC digital tomosynthesis retains the edge-enhancement observed in planar PC radiograph and further improves soft-tissue conspicuity by reducing the effects of superimposed tissue structure.
相衬(PC)边缘增强发生在不同组织的边界处,是一种干涉效应,源于 X 射线穿过两种组织时获得的不同相位偏移。虽然在平面相衬射线照片中可以观察到,但数字断层合成对这种边缘增强效应的影响以前没有报道过。本工作的目的是证明:(1)使用传统的 X 射线源可以进行相衬数字断层合成(PC-DTS);(2)与平面相衬射线照片相比,重建的断层合成图像显示并保留了边缘增强;(3)断层合成通过减少叠加结构的影响来提高物体对比度。
使用未经修改的商用柜式 X 射线系统(Faxitron LX-60)。该系统包含一个钨阳极 X 射线管,在拍摄每张 PC 射线照片时以 24 kVp 和 3 mAs 运行,标称焦点尺寸为 0.010 毫米。数字探测器使用 CsI/CMOS,像素尺寸为 0.054 毫米×0.054 毫米。要成像的物体附着在计算机控制的旋转电机上,并以每度 1 度的增量围绕中心位置旋转 +/-25 度。在每个增量处,拍摄三张相衬射线照片,然后平均以减少噪声的影响。然后使用这些平面图像重建一系列 56 个纵向断层合成图像,图像偏移增量约为 0.7 毫米。
断层合成 z 平面分辨率测量约为 4 毫米。与平面 PC 图像相比,断层合成图像被证明保留了 PC 边界边缘增强,并且物体对比度得到改善。
我们的工作表明,PC 数字断层合成保留了在平面 PC 射线照片中观察到的边缘增强,并且通过减少叠加组织结构的影响进一步提高了软组织的可见度。