Fouad-Tarazi F M
Cleveland Clinic Foundation, OH 44195-5069.
Herz. 1990 Dec;15(6):393-8.
Radionuclide ventriculography has been used for the assessment of left ventricular diastolic function in hypertension. Compared to cardiac Doppler ultrasound techniques, the radionuclide method offers the advantages of allowing numerous consecutive cardiac cycles to be examined, and of deriving the data of these examinations from automated software computer programs. For better precision, however, adequate instrumentation is required. In addition, correction factors should be applied to overcome the influence of elements such as heart rate, left ventricular end-diastolic volume, as well as the technical influence of the efficiency of counting among individuals. Its application to hypertensive patients enabled the diagnosis of early abnormalities of left ventricular filling rate in about 30% of the population studied before any alteration in indices of systolic function were detected. The mechanism of the alteration of these indices of diastolic filling rate in hypertension, however, is still not well understood.
放射性核素心室造影已用于评估高血压患者的左心室舒张功能。与心脏多普勒超声技术相比，放射性核素方法具有允许检查多个连续心动周期以及从自动化软件计算机程序获取这些检查数据的优点。然而，为了获得更高的精度，需要有足够的仪器设备。此外，应应用校正因子以克服心率、左心室舒张末期容积等因素的影响，以及个体间计数效率的技术影响。将其应用于高血压患者，能够在检测到收缩功能指标出现任何改变之前，在约30%的研究人群中诊断出左心室充盈率的早期异常。然而，高血压患者舒张充盈率这些指标改变的机制仍未完全明了。
