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与化学刺激引起的体温控制有关的下丘脑肾上腺素能受体。

Hypothalamic adrenoceptors concerned with control of temperature, elicited by chemical stimulation.

作者信息

Mehta V, Chakrabarty A S, Chabra I P

机构信息

Department of Physiology, Maulana Azad Medical College, New Delhi, India.

出版信息

Indian J Exp Biol. 1990 Oct;28(10):989-91.

PMID:2177727
Abstract

Norepinephrine (NE) and its blockers (alpha-1, alpha-2, beta-1 and beta-2) were micro-injected into the anterior hypothalamus of male albino rats and the effects of these injections on rectal temperature were recorded. The results indicated that the thermoregulatory effects of NE were dependent on ambient temperature. The present study further demonstrated the specific involvement of beta-2 receptors present in the anterior hypothalamus concerned with thermoregulation.

摘要

将去甲肾上腺素(NE)及其阻滞剂(α-1、α-2、β-1和β-2)微量注射到雄性白化大鼠的下丘脑前部,并记录这些注射对直肠温度的影响。结果表明,NE的体温调节作用取决于环境温度。本研究进一步证明了下丘脑前部存在的与体温调节有关的β-2受体的具体参与情况。

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