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[从长春花属植物中提取具有药理活性的生物碱]

[Extraction of pharmacologically active alkaloids from Vinca species].

作者信息

Gagua N D, Bakuridze A D, Vachnadze N S, Berashvili D T, Vachnadze V Iu

出版信息

Georgian Med News. 2011 Jun(195):105-10.

Abstract

From the Genius Vinca the drugs have been received, arbitrally named: Vingerbin- with anthyarithmic activity, Vincabral-for improvement of brain blood circulation and leicobetin-as stimulator of leicopoesis. The investigations has been performed for creation of rational, resource saving, rentable phyto technologies. As a result, the liquid extraction general schema is provided for receipt of indolic alkaloids from plants V. herbaceae and V.minor. Analyses have shown that extraction with diluent gaz gives the possibility to receive the sums rich with alkaloids:Vingerbin and Vincabral. The advantage of extraction with diluent gaz is exclusion of high volumes of organic and non organic chemicals on the stage of extraction from raw material and liquid extraction, and remain and lipofil fraction converse to new phytosubtances for receipt of biologically active flavonoids, amino acids etc.

摘要

从天才长春花中提取了一些药物,它们被随意命名:具有抗心律失常活性的长春宾、用于改善脑血液循环的长春布拉尔以及作为白细胞生成刺激剂的白细胞生成素。为了创建合理、节约资源且有利可图的植物技术,已经开展了相关研究。结果,提供了从草本长春花和小长春花中提取吲哚生物碱的液体提取通用方案。分析表明,用稀释气体进行提取能够得到富含生物碱的提取物:长春宾和长春布拉尔。用稀释气体进行提取的优势在于,在从原料和液体提取物中提取的阶段排除了大量有机和无机化学物质,并且剩余的脂溶性部分转化为新的植物物质以获取生物活性黄酮类化合物、氨基酸等。

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