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[简化双99mTc标记法诊断肝血管瘤]

[Diagnosis of hepatic hemangioma with simplified double 99mTc labelling].

作者信息

Piga M, Satta L, Loi G, Montaldo C, Schiffini P, Careddu A, Dore F, Corrias M, Madeddu G

机构信息

Centro di Medicina Nucleare, Università, Cagliari.

出版信息

Radiol Med. 1990 Dec;80(6):912-4.

PMID:2177904
Abstract

The authors report on their experience with liver hemangioma (LH) diagnosis by means of a simplified method--that is, the simultaneous, in vivo, double labelling of liver reticuloendothelial system (RES) and of red blood cells (RBC) by 99mTc. Twenty-eight patients with US diagnosis of suspected LH and 15 controls were examined after sequential iv injection of SnCl2, of 99mTc-mucolloid albumin and, after liver scintigraphy, of 99mTc-pertechnetate to conclude in vivo RBC labelling. All patients underwent CT and, if necessary, CT-guided biopsy. Focal colloid defects filled after RBC labelling were shown in 20/22 patients with unquestionable LH. No colloid defects were shown in 6/28 cases (expansive process). 15/15 controls showed unchanged non-filling defects after double labelling. Finally, the authors point out that, in the diagnosis of LH, sequential double labelling of liver RES and RBC appears to be a quicker scintigraphic technique than conventional ones. Moreover, this technique has the same high specificity and sensitivity as more time-consuming ones.

摘要

作者报告了他们使用一种简化方法诊断肝血管瘤(LH)的经验,即通过99mTc对肝网状内皮系统(RES)和红细胞(RBC)进行体内同步双重标记。在依次静脉注射氯化亚锡、99mTc - 胶体白蛋白后,以及在肝脏闪烁扫描后注射高锝酸盐以完成体内红细胞标记,对28例超声诊断疑似LH的患者和15例对照进行了检查。所有患者均接受了CT检查,必要时进行CT引导下活检。在22例确诊为LH的患者中,有20例在红细胞标记后显示局灶性胶体缺损被填充。28例中有6例(占位性病变)未显示胶体缺损。15例对照在双重标记后显示未填充缺损无变化。最后,作者指出,在LH的诊断中,肝RES和RBC的序贯双重标记似乎是一种比传统方法更快的闪烁扫描技术。此外,该技术与耗时更长的技术具有相同的高特异性和敏感性。

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