Department of Radiology, Faculty of Medicine, Islamic Azad University-Mashhad Branch, Mashhad, Iran.
Arch Gynecol Obstet. 2012 Jan;285(1):255-8. doi: 10.1007/s00404-011-1986-7. Epub 2011 Jul 22.
Preterm delivery is one of the important causes of morbidity and mortality in newborns. Nowadays, a new sonographic marker is suggested for prediction of preterm delivery which is termed "Cervical Gland Area" (CGA). Absence of normal mucosal glands of the cervix can be utilized as a predictor in preterm delivery. This study was performed to evaluate the role of absence of CGA for the prediction of preterm delivery <37 weeks.
Trans-vaginal ultrasonography was performed on 600 pregnant women at 16-19 weeks of gestational age. Cervical gland area and cervical length were evaluated. Women with cervical length <25 mm were conducted to cerclage and excluded from the study. Age, number of pregnancies and history of previous preterm deliveries were recorded in questionnaires. The date of delivery was recorded. Statistical analysis was performed by version 18 SPSS and P value <0.05 was significant.
Spontaneous preterm delivery was seen in 6.7% of all women. There was no significant difference in age, cervical length, the number of pregnancies and history of previous preterm deliveries between term pregnancies and preterm cases. CGA was detected in 77.1% of term pregnancies comparing with 55% in preterm group; which was significantly different (P value = 0.002).
Non detection of CGA at second trimester ultrasonography is a predictor of preterm delivery.
早产是新生儿发病和死亡的重要原因之一。目前，一种新的超声标志物被提出用于预测早产，称为“宫颈腺面积”（CGA）。宫颈黏膜腺体的缺失可用作早产的预测指标。本研究旨在评估 CGA 缺失在预测<37 周早产中的作用。
对 600 名 16-19 周妊娠的孕妇进行经阴道超声检查。评估宫颈腺面积和宫颈长度。宫颈长度<25mm 的孕妇行宫颈环扎术，并排除在研究之外。在问卷中记录年龄、妊娠次数和既往早产史。记录分娩日期。采用 SPSS 18 版进行统计学分析，P 值<0.05 为有统计学意义。
所有孕妇自发性早产发生率为 6.7%。足月妊娠与早产组在年龄、宫颈长度、妊娠次数和既往早产史方面无显著差异。足月妊娠组中 CGA 的检出率为 77.1%，早产组为 55%，差异有统计学意义（P 值=0.002）。
中孕期超声检查未检测到 CGA 是早产的预测指标。
