有意诱导的旋流流动可能改善冠状动脉分叉支架的血液动力学性能。
Intentionally induced swirling flow may improve the hemodynamic performance of coronary bifurcation stenting.
机构信息
Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.
出版信息
Catheter Cardiovasc Interv. 2012 Feb 15;79(3):371-7. doi: 10.1002/ccd.22969. Epub 2011 Jul 21.
OBJECTIVES AND BACKGROUND
Bifurcation stenting represents a challenge for the high rate of restenosis that has close correlations with local hemodynamics. This study sought to test the hypothesis that by intentionally inducing swirling flow the hemodynamic performance of bifurcation stenting can be improved.
METHODS
The hemodynamics of bifurcation stenting with and without swirling flows were numerically simulated and compared.
RESULTS
The results revealed that swirling flow significantly suppressed flow disturbance of blood at the bifurcation and WSS at two critical regions, the outer wall of the bifurcation ostium and the floor wall opposite the branching, was enhanced.
CONCLUSIONS
This study therefore suggests that intentionally inducing swirling flow might be a good strategy in bifurcation stenting.
目的和背景
分叉支架置入术存在较高的再狭窄率，这与局部血流动力学密切相关，是一个挑战。本研究旨在验证以下假设，即通过有意诱导旋流，可以改善分叉支架置入术的血流动力学性能。
方法
数值模拟并比较了存在和不存在旋流的分叉支架置入术的血流动力学。
结果
结果表明，旋流显著抑制了分叉处的血液流动干扰，同时增强了两个关键区域的壁面切应力，这两个区域分别是分叉口的外壁和分支相对的底部壁面。
结论
因此，本研究表明，有意诱导旋流可能是分叉支架置入术中的一种有效策略。
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