[Assaying the SCF platelets cyclic nucleotides of schizophrenics and analyzing its correlation with pathopschological factors].

The experiment adopted radioimmunoassay to assay CSF, platelets cAMP cGMP levels of a group of Schizophrenia patients, and made a correlation analysis between the cAMP, cGMP and the evaluated factor scores of BPRS and SCL-90. The results showed: (1)CSF cAMP level of Schizophrenics was significantly higher than normal controls; (2)There was a significantly positive correlation between CSF cAMP and BPRS factor 1, a significantly negative correlation between platelets cAMP and BPRS factor 3, a significantly positive correlation between CSF cAMP and SCL-90 factor 5,8. The paper discussed the similarities and differences between the results of this experiment and the former studies.