Laboratoire Hospitalo-Universitaire de Parasitologie-Mycologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.
Clin Microbiol Infect. 2011 Oct;17(10):1492-4. doi: 10.1111/j.1469-0691.2011.03568.x. Epub 2011 Jul 22.
Diaporthe phaseolorum (syn. Phomopsis phaseoli) is a frequent fungal parasite of plants, present on all continents around the world. It has rarely been involved in human diseases. We report a case of eumycetoma with osteomyelitis of the forefoot caused by this fungus and diagnosed by molecular biology. The patient had positive HTLV-1 serology and was a farmer from French Guiana who walked barefoot. He was successfully treated with long-term oral itraconazole (400 mg/day). A review of the literature underlines the essential roles of plants and host immunosuppression in this infection and the favourable outcome with a triazole antifungal treatment.
菜豆壳球孢菌（同义名：菜豆拟茎点霉）是一种常见的植物寄生真菌，分布于全球各大洲。它很少引起人类疾病。我们报告了一例由该真菌引起的足前部骨髓炎的真菌性足菌肿病例，并通过分子生物学方法进行了诊断。患者的 HTLV-1 血清学检测呈阳性，是一名来自法属圭亚那的农民，赤脚务农。他接受了长期的口服伊曲康唑（400mg/天）治疗，取得了成功。对文献的回顾强调了植物和宿主免疫抑制在这种感染中的重要作用，以及三唑类抗真菌治疗的良好预后。
