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激光原位角膜磨镶术后迟发性产酸克雷伯菌瓣缘相关角膜溃疡。

Late-onset Klebsiella oxytoca flap-margin-related corneal ulcer following laser in situ keratomileusis.

机构信息

Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

出版信息

J Cataract Refract Surg. 2011 Aug;37(8):1551-4. doi: 10.1016/j.jcrs.2011.05.016.

DOI:10.1016/j.jcrs.2011.05.016
PMID:21782101
Abstract

A 45-year-old woman developed a spontaneous flap-margin-related corneal ulcer 11 years after the original laser in situ keratomileusis (LASIK) procedure. Two enhancements had been performed; the most recent was 3 years prior to presentation. Cultures were positive for a heavy growth of Klebsiella oxytoca. The ulcer responded clinically to topical treatment with fortified cefazolin. Eighteen days after presentation, the infiltrate had resolved and the cornea had fully epithelialized. To our knowledge, this is the first report of post-LASIK infectious keratitis caused by K oxytoca.

摘要

一位 45 岁女性在最初的激光原位角膜磨镶术(LASIK)后 11 年出现自发性瓣缘相关角膜溃疡。曾进行过两次增强手术;最近一次是在就诊前 3 年。培养结果为产酸克雷伯菌大量生长。溃疡经头孢唑啉强化局部治疗后临床症状得到缓解。就诊后 18 天,浸润消退,角膜完全上皮化。据我们所知,这是首例由产酸克雷伯菌引起的 LASIK 后感染性角膜炎报告。

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Klebsiella oxytoca Complex: Update on Taxonomy, Antimicrobial Resistance, and Virulence.产酸克雷伯菌复合体:分类学、抗菌耐药性和毒力的最新研究进展。
Clin Microbiol Rev. 2022 Jan 19;35(1):e0000621. doi: 10.1128/CMR.00006-21. Epub 2021 Dec 1.
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A case of late-onset Klebsiella oxytoca keratitis treated with topical imipenem after deep anterior lamellar keratoplasty.深板层角膜移植术后应用替莫培南滴眼治疗迟发性产酸克雷伯菌角膜炎 1 例
Arq Bras Oftalmol. 2021 May-Jun;84(3):279-281. doi: 10.5935/0004-2749.20210043.
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Very late-onset flap margin corneal ulcer following laser in situ keratomileusis.
准分子原位角膜磨镶术后迟发性角膜瓣边缘溃疡
Int Ophthalmol. 2019 Nov;39(11):2533-2538. doi: 10.1007/s10792-019-01100-0. Epub 2019 Apr 13.