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美国活体供肾移植——回顾与展望。

Living donor kidney transplantation in the United States--looking back, looking forward.

机构信息

Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA.

出版信息

Am J Kidney Dis. 2011 Sep;58(3):343-8. doi: 10.1053/j.ajkd.2011.06.007. Epub 2011 Jul 23.

DOI:10.1053/j.ajkd.2011.06.007
PMID:21783290
Abstract

There is a desperate need for kidney donors. Twenty-five years ago, we urged more widespread acceptance of unrelated living donors for kidney transplantation. Since then, 2 of us have donated a kidney to an unrelated recipient. In our view, the major challenges for living donor transplantation today are to improve access to this extraordinary gift of life and ensure its safety. Our perspective is that altruism is the motivation for most living kidney donors and the decision to donate represents a shared responsibility among the donor, the donor's physician, and the team of professionals at the transplant center. Thus, sound knowledge of the benefits and risks to donors and recipients is required for informed decisions, and all parties share in the responsibility for the outcomes after living kidney donation. We encourage our colleagues and agencies within the US Department of Health and Human Services to accept the responsibility to do their utmost to provide access to this life-enhancing procedure and systematically evaluate the safety of kidney donation as it evolves to meet the needs of more of our patients.

摘要

目前非常急需肾脏捐献者。25 年前,我们曾大力提倡更广泛地接受非亲属活体供者进行肾脏移植。从那以后,我们中的 2 人向非亲属受者捐献了肾脏。在我们看来,目前活体供肾移植的主要挑战是改善获取这种非凡的生命礼物的途径,并确保其安全性。我们认为,利他主义是大多数活体肾脏捐献者的动机,捐献决定代表着捐献者、捐献者的医生和移植中心专业团队之间的共同责任。因此,为了做出明智的决策,需要充分了解供者和受者的获益和风险,并且在活体肾脏捐献后,所有各方都要共同承担结果的责任。我们鼓励我们在美国卫生与公众服务部的同事和机构承担起责任,尽最大努力提供这种增强生命的程序,并系统地评估肾脏捐献的安全性,因为随着它的发展,要满足更多患者的需求,其安全性也需要不断改进。

相似文献

1
Living donor kidney transplantation in the United States--looking back, looking forward.美国活体供肾移植——回顾与展望。
Am J Kidney Dis. 2011 Sep;58(3):343-8. doi: 10.1053/j.ajkd.2011.06.007. Epub 2011 Jul 23.
2
Gift exchange and organ donation: donor and recipient experiences of live related kidney transplantation.礼物交换与器官捐赠:亲属活体肾移植中供体与受体的经历
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Responding to offers of altruistic living unrelated kidney donation by group associations: an ethical analysis.团体协会对利他性活体非亲属肾捐赠提议的回应:一项伦理学分析。
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The UNOS OPTN waiting list and donor registry.器官共享联合网络(UNOS)的器官分配等待名单及捐赠者登记系统。
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Emotional and Financial Experiences of Kidney Donors over the Past 50 Years: The RELIVE Study.过去50年肾脏捐献者的情感与经济经历:重温研究
Clin J Am Soc Nephrol. 2015 Dec 7;10(12):2221-31. doi: 10.2215/CJN.07120714. Epub 2015 Oct 13.
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Could living unrelated renal transplantation ameliorate the actual shortage of organs in the Balkan region?
非亲属活体肾移植能否缓解巴尔干地区实际存在的器官短缺问题?
Hippokratia. 2013 Jul;17(3):243-5.
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State of the art of robotic surgery in organ transplantation.器官移植中机器人手术的技术现状。
World J Surg. 2013 Dec;37(12):2791-9. doi: 10.1007/s00268-013-2244-x.
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Donor and recipient size mismatch in adolescents undergoing living-donor renal transplantation affect long-term graft survival.青少年活体供肾移植中供受者体型不匹配影响长期移植物存活率。
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Protective effect of zinc-N-acetylcysteine on the rat kidney during cold storage.锌-N-乙酰半胱氨酸对大鼠肾脏冷藏期间的保护作用。
Am J Physiol Renal Physiol. 2013 Oct 1;305(7):F1022-30. doi: 10.1152/ajprenal.00532.2012. Epub 2013 Jul 3.
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Innovative strategies in living donor kidney transplantation.活体供肾移植的创新策略。
Nat Rev Nephrol. 2012 May 1;8(6):332-8. doi: 10.1038/nrneph.2012.82.