Nagai T, Takaba H, Miyake K
Department of Urology, Nagoya University School of Medicine.
Hinyokika Kiyo. 1990 Jan;36(1):91-5.
A 37-year-old man consulted our hospital with a complaint of male infertility. He was masculine but 159.9 cm in height. His beard, axillary hair and pubic hair were all normal. The penis and scrotum were also normal, but bilateral testes were very small (1 ml. respectively). Semen analysis revealed azoospermia. Endocrinological examination showed elevated serum lactating hormone and follicle stimulating hormone level, and extremely low level of serum testosterone. Testicular biopsy disclosed severely hyalinized seminiferous tubules and hyperplasia of Leydig cells. No ovarian tissue could be detected. The chromosomal analysis revealed a karyotype of 46 XX. This case was diagnosed as a case of 46XX male. The Japanese literature of 46XX male is reviewed.
一名37岁男性因男性不育前来我院就诊。他具有男性特征，但身高为159.9厘米。其胡须、腋毛和阴毛均正常。阴茎和阴囊也正常，但双侧睾丸非常小（分别为1毫升）。精液分析显示无精子症。内分泌检查显示血清催乳素和卵泡刺激素水平升高，血清睾酮水平极低。睾丸活检显示生精小管严重玻璃样变和睾丸间质细胞增生。未检测到卵巢组织。染色体分析显示核型为46,XX。该病例被诊断为46,XX男性。本文对日本有关46,XX男性的文献进行了综述。
