几种鲸鱼促肾上腺皮质激素的分离及一级结构

Isolation and primary structure of adrenocorticotropin from several species of whale.

作者信息

Kawauchi H, Muramoto K, Ramachandran J

出版信息

Int J Pept Protein Res. 1978 Nov;12(5):318-24. doi: 10.1111/j.1399-3011.1978.tb02903.x.

DOI:10.1111/j.1399-3011.1978.tb02903.x

Abstract

The isolation of adrenocorticotropin (ACTH) from fin (Balaenoptera physalus), sei (Blaenoptera borelis) and sperm (Physeter catodon) whale pituitaries is described. Their primary structures have been elucidated by the fluorescein isothiocyanate method and revealed to be identical to the structure of the human hormone. Fin whale exhibited an identical steroidogenic activity to that of the porcine hormone.

摘要

描述了从鳍鲸（南极鲸）、塞鲸和抹香鲸的垂体中分离促肾上腺皮质激素（ACTH）的过程。通过异硫氰酸荧光素法阐明了它们的一级结构，结果显示与人类激素的结构相同。鳍鲸表现出与猪激素相同的类固醇生成活性。