Department of Radiology, University of Texas Health Science Center at San Antonio, TX, USA.
AJR Am J Roentgenol. 2011 Aug;197(2):W286-94. doi: 10.2214/AJR.10.5415.
This article provides a comprehensive review of the role of MDCT and MRI in the diagnosis of drug-induced complications in the abdomen and pelvis in adults. A systematic organ-based review of these complications is presented, including but not limited to hepatic changes after chemotherapy, renal complications such as tumor lysis syndrome and lithium nephropathy, gastrointestinal manifestations, various opportunistic infections and secondary neoplasms, mycotic aortic aneurysm from intravesical bacille Calmette-Guérin, complications of anticoagulant therapy, and oral contraceptives.
Advancements in imaging have led to recognition of radiologic features of previously unsuspected diseases. Occasionally, imaging may also identify effects of treatments instituted for these diseases. Consequently, imaging plays a critical role in the accurate diagnosis of a broad spectrum of drug-induced complications in the abdomen, both in emergent and nonemergent settings. Knowledge of the natural history, clinical manifestations, and salient imaging features of these entities is crucial to facilitate accurate clinical diagnosis in a timely fashion.
本文全面回顾了 MDCT 和 MRI 在诊断成人腹部和盆腔药物引起的并发症方面的作用。本文对这些并发症进行了系统的器官为基础的综述，包括但不限于化疗后的肝改变、肿瘤溶解综合征和锂肾病等肾并发症、胃肠道表现、各种机会性感染和继发肿瘤、膀胱内卡介苗引起的真菌性主动脉瘤、抗凝治疗和口服避孕药的并发症。
影像学的进步导致了以前未被怀疑的疾病的放射学特征的认识。偶尔，影像学也可以识别出这些疾病的治疗效果。因此，在急诊和非急诊情况下，影像学在准确诊断腹部广泛的药物引起的并发症中都起着至关重要的作用。了解这些疾病的自然病史、临床表现和显著的影像学特征对于及时准确的临床诊断至关重要。
