年轻癌症相关性截肢患者的幻肢痛：圣裘德儿童研究医院的近期经验。
Phantom limb pain in young cancer-related amputees: recent experience at St Jude children's research hospital.
机构信息
Department of Children's Anaesthesia, Women's and Children's Hospital, Adelaide, Australia.
出版信息
Clin J Pain. 2012 Mar-Apr;28(3):222-5. doi: 10.1097/AJP.0b013e318227ce7a.
OBJECTIVES
This study in children and young adults having cancer-related amputation aimed to examine the incidence of phantom limb pain (PLP) in the first year after amputation and also the proportion of patients who had preamputation pain.
METHODS
A retrospective review of medical records was undertaken. The proportion of patients with PLP was reported. Fisher exact test was used to examine the association between PLP and the presence of preamputation pain and between PLP and age (≤ 18 y vs. >18 y).
RESULTS
Twenty-six amputations were performed on 25 patients. During the year after amputation, 76% of patients had experienced PLP at some time. After 1 year, though, only 10% still had PLP. Preamputation pain was present in 64% of patients. Although both of our patients with PLP at 1 year were young adults (older than or equal to 18 y) and both had preamputation pain, we found no statistically significant associations between age or the presence of preamputation pain with PLP.
DISCUSSION
PLP after cancer-related amputation in children and young adults seems to be common but generally short lived in most patients.
目的
本研究旨在探讨儿童和青少年癌症截肢患者截肢后一年内幻肢痛（PLP）的发生率，并评估有术前疼痛患者的比例。
方法
对病历进行回顾性分析。报告有 PLP 患者的比例。Fisher 确切检验用于检验 PLP 与术前疼痛的存在以及 PLP 与年龄（≤ 18 岁与>18 岁）之间的关系。
结果
25 名患者共进行了 26 次截肢。截肢后一年内，76%的患者曾经历过 PLP。然而，1 年后，只有 10%的患者仍有 PLP。64%的患者有术前疼痛。尽管我们有 2 名在 1 年后仍有 PLP 的患者都是年轻成人（≥ 18 岁），并且都有术前疼痛，但我们发现年龄或术前疼痛的存在与 PLP 之间没有统计学上的显著关联。
讨论
儿童和青少年癌症相关截肢后发生 PLP 似乎很常见，但在大多数患者中通常是短暂的。
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