Fernández-Torres R, Verea M M, Alvarez A, Torres P, Fonseca E
Departments of Dermatology, Complejo Hospitalario Universitario A Coruña, Sir John Moore S/N, 15001 La Coruña, Spain.
Dermatol Res Pract. 2011;2011:385074. doi: 10.1155/2011/385074. Epub 2011 Jul 11.
The development of a second haematological disease during the course of systemic mastocytosis is a well-known phenomenon. In most of the cases, they consist of myelodysplasia or myeloproliferative disorders. The association with lymphoproliferative disorders has also been described, but it is uncommon and the relationship is not well established. We report a patient diagnosed with systemic mastocytosis who three years later developed a splenic marginal zone lymphoma with villous lymphocytes.
在系统性肥大细胞增多症病程中出现第二种血液系统疾病是一种众所周知的现象。在大多数情况下，它们包括骨髓发育异常或骨髓增殖性疾病。与淋巴增殖性疾病的关联也有描述，但并不常见且关系尚未明确确立。我们报告一例诊断为系统性肥大细胞增多症的患者，三年后发展为伴有绒毛状淋巴细胞的脾边缘区淋巴瘤。
