Clothier R H, Worley R T, Balls M
J Anat. 1978 Dec;127(Pt 3):491-504.
The renal corpuscle and segments of the renal tubule of the urodele amphibian Amphiuma means have been described and studied by light and electron microscopy as a background for investigations on the effects of hormones, drugs, toxins and carcinogens on cell structure and function in long-term organ cultures of kidney explants. Notable features of the A. means kidney include the number and variety of cytoplasmic inclusions in the cells of the proximal segment, the comparatively thick glomerular filter, and the presence of possible renin granules in the endothelial cells lining the afferent arteriole near its point of entry to the glomerular capsule.
为了研究激素、药物、毒素和致癌物对肾外植体长期器官培养中细胞结构和功能的影响，人们已用光镜和电镜对有尾两栖动物蚓螈（Amphiuma means）的肾小体和肾小管各段进行了描述和研究。蚓螈肾的显著特征包括近端段细胞中细胞质内含物的数量和种类、相对较厚的肾小球滤过器，以及在入球小动脉进入肾小球囊的入口处附近的内皮细胞中可能存在的肾素颗粒。
