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[代偿性肥大过程中肾小管某些细胞质成分数量和结构的改变]

[Modification of the number and structure of certain cytoplasmic components of the renal tubules during compensatory hypertrophy].

作者信息

Kazimierczak J, Bucher O

出版信息

Bull Assoc Anat (Nancy). 1976 Mar;60(168):145-50.

PMID:189864
Abstract

In the remaining kidney of unilaterally nephrectomised three to six months old Wistar rats, the measurement of the external and internal diameters indicated an increase in size of both proximal and distal convoluted tubules, although less distinct in the latter. Stereomorphometric measurements of the chondriome and the cytoplasmic inclusions (lysosomes, phagosomes, peroxisomes, etc.) have shown, as compared with similar tests in shamoperated animals, changes in the volumes of these components which can be related to the increase of enzymatic activities reported earlier. However, no obvious changes of the general ultrastructure of the kidneys undergoing hypertrophy could be observed.

摘要

在单侧肾切除三至六个月大的Wistar大鼠的剩余肾脏中,对近端和远端曲管的外径和内径测量表明,两者的尺寸均有所增加,尽管后者不太明显。与假手术动物的类似测试相比,对线粒体和细胞质内含物(溶酶体、吞噬体、过氧化物酶体等)的立体形态测量显示,这些成分的体积发生了变化,这可能与先前报道的酶活性增加有关。然而,未观察到发生肥大的肾脏的一般超微结构有明显变化。

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