Queen Elizabeth Hospital, South London Healthcare NHS Trust, Stadium Road, London, SE18 4QH, UK,
Curr Infect Dis Rep. 2011 Oct;13(5):478-84. doi: 10.1007/s11908-011-0201-0.
Septic arthritis is a common rheumatological emergency requiring prompt diagnosis and treatment, since delays in management can lead to high morbidity and mortality. In this review article, we discuss the epidemiology and recent advances in knowledge of the pathogenesis of septic arthritis, with a special emphasis on various bacterial and host factors involved in mediating the inflammatory process and the potential for targeted therapy to modulate the immune response. Recent advances in laboratory and imaging techniques are reviewed along with treatment and potential new therapies.
脓毒性关节炎是一种常见的风湿学急症，需要及时诊断和治疗，因为治疗延误可能导致高发病率和死亡率。在这篇综述文章中，我们讨论了脓毒性关节炎的流行病学和发病机制的最新进展，特别强调了各种细菌和宿主因素在介导炎症过程中的作用以及靶向治疗调节免疫反应的潜力。还回顾了实验室和影像学技术的最新进展以及治疗和潜在的新疗法。
