[静息状态下乳头肌稳态与松弛弹性特性的建模]

[Modeling of steady-state and relaxation elastic properties of the papillary muscle at rest].

作者信息

Kobelev A V, Smoliuk L T, Lukin O N, Balakin A A, Protsenko Iu L

出版信息

Biofizika. 2011 May-Jun;56(3):534-42.

Abstract

The biomechanical modeling of a papillary muscle preparation as an adequate object for studying the properties of the myocardial tissue under uniaxial stretching has been performed. The steady-state and relaxation tests of the papillary muscle of laboratory animals (rabbit and rat) have been conducted in normal conditions and after the maceration of intracellular structures with high ionic strength solution. It has been shown that the main contribution to the viscoelastic properties in the initial range of physiological deformations is made by the connective tissue skeleton, whereas under large physiological deformations, by intracellular structures.

摘要

已经进行了将乳头肌制备作为研究单轴拉伸下心肌组织特性的合适对象的生物力学建模。在正常条件下以及用高离子强度溶液浸解细胞内结构后，对实验动物（兔子和大鼠）的乳头肌进行了稳态和松弛测试。结果表明，在生理变形的初始范围内，对粘弹性特性的主要贡献来自结缔组织骨架，而在较大的生理变形下，则来自细胞内结构。