Weshler Z, Breuer R, Or R, Naparstek E, Pfeffer M R, Lowental E, Slavin S
Department of Radiation, Hadassah University Hospital, Jerusalem, Israel.
Br J Haematol. 1990 Jan;74(1):61-4. doi: 10.1111/j.1365-2141.1990.tb02538.x.
The potential beneficial effects of partial lung shielding were investigated in 44 patients conditioned by whole body radiotherapy as part of the conditioning for bone marrow transplantation (BMT). The first 23 patients were irradiated with fractionated total body irradiation (TBI) to a total dose of 12 Gy. In the second series of 21 patients a 50% transmission lung shield was utilized following 6 Gy TBI. This treatment was combined in the second group with four fractions of 1.5 Gy total lymphoid irradiation (TLI), given in 2 d. The rate of idiopathic interstitial pneumonitis (IP) was 26% in the first group, compared to none in the second.
在44例接受全身放疗作为骨髓移植（BMT）预处理一部分的患者中，研究了部分肺屏蔽的潜在有益效果。前23例患者接受分次全身照射（TBI），总剂量为12 Gy。在第二组21例患者中，在6 Gy TBI后使用了50%透射率的肺屏蔽。在第二组中，这种治疗与分4次给予、每次1.5 Gy的全身淋巴结照射（TLI）相结合，在2天内完成。第一组特发性间质性肺炎（IP）的发生率为26%，而第二组无一例发生。
