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[法国一家大学医院医护人员中2009年季节性和甲型(H1N1)大流行性流感疫苗接种覆盖率]

[Seasonal and pandemic A (H1N1) 2009 influenza vaccination coverage among health-care workers in a French university hospital].

作者信息

Boyeau Cécile, Tanguy Maurice, Pean Stéphanie, Delhumeau Alain, Fanello Serge

机构信息

Service des Admissions et Urgences, CHU Angers, 4, Rue Larrey, 49933 Angers cedex 09.

出版信息

Sante Publique. 2011 Jan-Feb;23(1):19-29.

PMID:21786736
Abstract

The aim of this study was to highlight the perceived risk, behavioural changes and acceptance of the seasonal and pandemic (H1N1) 2009 influenza vaccine by healthcare workers in a French teaching hospital. We surveyed healthcare workers from the Angers French teaching hospital (CHU) using a cross-sectional intercept design during phase 5A of the French National Plan for the Prevention and Control of the 2009 "Pandemic Influenza". Professionals were asked to take the survey in their workplace from November 2009 to February 2010. The primary endpoint was immunization coverage among healthcare workers who had contact with at-risk patients. Among the 532 workers responding, 22.3% were vaccinated against seasonal influenza and 36.5% against H1N1 influenza. The immunization coverage rate was significantly higher among physicians. For seasonal influenza, the 2 most-cited reasons for vaccination were "to protect the patient" and "to avoid getting sick"; arguments against vaccination were "I never get the flu" or "getting vaccinated is inconvenient and takes too long". For the pandemic A (H1N1) 2009 flu, the arguments for vaccination were "to protect the patient" and "to protect the family"; arguments against vaccination were linked to vaccine safety. Vaccination coverage against seasonal influenza was lower than that reported in the literature, possibly because of the time required between vaccination for pandemic (H1N1) 2009 influenza and seasonal influenza and the priority often given to vaccination against H1N1. This study emphasizes the lack of perception of pandemic (H1N1) 2009 influenza severity and lack of understanding about the process of developing the seasonal and H1N1 influenza vaccines. Concerns about safety, the possibility of side effects and the vaccine development process need to be addressed. An information campaign stressing the necessity for healthcare workers to be vaccinated must be strengthened.

摘要

本研究旨在突出法国一家教学医院的医护人员对季节性流感疫苗和2009年大流行甲型(H1N1)流感疫苗的感知风险、行为变化及接受情况。在法国2009年“大流行性流感”预防与控制国家计划的5A阶段,我们采用横断面拦截设计对昂热法国教学医院(CHU)的医护人员进行了调查。2009年11月至2010年2月期间,要求专业人员在其工作场所接受调查。主要终点是接触高危患者的医护人员的免疫接种覆盖率。在532名回复的工作人员中,22.3%接种了季节性流感疫苗,36.5%接种了甲型H1N1流感疫苗。医生的免疫接种覆盖率显著更高。对于季节性流感,接种疫苗最常提到的两个原因是“保护患者”和“避免生病”;反对接种的理由是“我从不患流感”或“接种疫苗不方便且耗时太长”。对于2009年大流行甲型(H1N1)流感,接种疫苗的理由是“保护患者”和“保护家人”;反对接种与疫苗安全性有关。季节性流感疫苗接种覆盖率低于文献报道水平,这可能是由于2009年大流行甲型(H1N1)流感疫苗接种与季节性流感疫苗接种之间所需的时间,以及通常优先接种甲型H1N1流感疫苗。本研究强调了对2009年大流行甲型(H1N1)流感严重性的认识不足以及对季节性流感和甲型H1N1流感疫苗研发过程的理解不足。对安全性、副作用可能性和疫苗研发过程的担忧需要得到解决。必须加强一场强调医护人员接种疫苗必要性的宣传活动。

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