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早熟物种 Chinchilla lanigera 耳蜗微音器和复合动作电位的产后发育。

Postnatal development of cochlear microphonic and compound action potentials in a precocious species, Chinchilla lanigera.

机构信息

Neuroscience Training Program and Department of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.

出版信息

J Acoust Soc Am. 2011 Jul;130(1):EL38-43. doi: 10.1121/1.3601881.

Abstract

The development of sound-evoked responses in Chinchilla lanigera was studied from postnatal ages P0-1 (first 24 h) to adult. Cochlear microphonic (CMs) and compound action potentials (CAPs), representing ensemble sound-evoked activities of hair cells and auditory nerve fibers, respectively, were present as early as age P0-1. The data indicate that CM thresholds and sensitivities were generally adult-like (i.e., fall into adult ranges) at birth, but suprathreshold CM amplitudes remained below adult ranges through P28. CAP thresholds reached adult-like values between P7-P14, but the suprathreshold CAP amplitude continued to increase until ∼P28. The results confirm the auditory precociousness of the chinchilla.

摘要

对幼年栗鼠(Chinchilla lanigera)从出生后 0-1 天(最初 24 小时)到成年的声诱反应发育进行了研究。耳蜗微音器电位(CMs)和复合动作电位(CAPs)分别代表毛细胞和听神经纤维的整体声诱活性,早在出生后 0-1 天就存在。数据表明,CM 阈值和灵敏度在出生时通常类似于成年(即落入成年范围),但超阈值 CM 幅度在 P28 之前仍低于成年范围。CAP 阈值在 P7-P14 之间达到成年水平,但超阈值 CAP 幅度持续增加直到约 P28。结果证实了栗鼠的听觉早熟。

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本文引用的文献

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Development of the middle ear in neonatal chinchillas. I. Birth to 14 days.
Acta Otolaryngol. 2000 Oct;120(8):922-32. doi: 10.1080/00016480050218645.
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Development of cochlear potentials in the neonatal gerbil.新生沙鼠耳蜗电位的发育
Hear Res. 1995 Apr;84(1-2):52-60. doi: 10.1016/0378-5955(95)00015-v.
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Audibility curve of the chinchilla.龙猫的听力曲线。
J Acoust Soc Am. 1970 Aug;48(2):513-23. doi: 10.1121/1.1912166.

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