University of Michigan College of Pharmacy, Ann Arbor, Michigan 48109-1065, USA.
Curr Opin Nephrol Hypertens. 2011 Sep;20(5):492-7. doi: 10.1097/MNH.0b013e328349c261.
Medication-related problems are very common in patients with chronic kidney disease (CKD). Identification, prevention and management of these problems require a comprehensive, interdisciplinary approach. This article reviews the recent literature regarding medication-related problems in CKD and proposes initiatives for addressing these problems through a structured review process and use of patient-centered adherence-promoting strategies.
Pharmacist-conducted medication review and intervention programs are successful at identifying and resolving medication-related problems in CKD patients. These programs are associated with a reduction in the number of medications and frequency of hospitalization, and are associated with maintenance of quality of life. However, adherence continues to be a major medication-related problem in CKD care.
Structured medication review and assessment of adherence assist in identification and resolution of medication-related problems in CKD. More research is needed on successful methods to improve medication adherence and related health outcomes.
药物相关问题在慢性肾脏病（CKD）患者中非常常见。识别、预防和管理这些问题需要综合的、跨学科的方法。本文回顾了最近关于 CKD 患者药物相关问题的文献，并提出了通过结构化审查流程和使用以患者为中心的促进药物使用策略来解决这些问题的举措。
药师进行的药物审查和干预计划在识别和解决 CKD 患者的药物相关问题方面非常成功。这些计划与减少药物数量和住院频率有关，并且与维持生活质量有关。然而，在 CKD 护理中，药物使用的依从性仍然是一个主要的药物相关问题。
结构化药物审查和对依从性的评估有助于识别和解决 CKD 患者的药物相关问题。需要进一步研究提高药物依从性和相关健康结果的成功方法。
