前列腺包膜保留根治性膀胱切除术：肿瘤安全性和临床结果。
Prostate capsule sparing radical cystectomy: oncologic safety and clinical outcome.
机构信息
Professor of Surgery, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Ave. #MG408, Toronto, Ontario M4N 3M5, Canada.
出版信息
Ther Adv Urol. 2009 Apr;1(1):43-50. doi: 10.1177/1756287209103921.
OBJECTIVES
Prostate capsule sparing radical cystectomy (PSRC) is a modification of the traditional surgical approach to radical cystectomy and neobladder, which offers the prospect of improved preservation of erectile function and continence.
METHODS
This is a review of the literature regarding the oncologic and quality of life outcomes of this approach for transitional cell carcinoma of the bladder, and a comparison of these results to conventional cystoprostatectomy and neobladder.
RESULTS
There are a limited number of studies addressing prostate capsule or prostate sparing cystectomy. All are retrospective, non-comparative and not uniform in terms of patient selection and technique. Long-term follow-up is lacking. The incidence of synchronous and or metachronous prostate cancer and TCC of the prostatic urethra is lower than that found in conventional cystoprostatectomy. This is likely due to pre-operative patient selection, restricting the procedure to those with no evidence of prostatic involvement by either disease. The local recurrence rate is 5%, comparable to standard cystoprostatectomy. Recurrence free and overall survival rates are comparable.
目的
前列腺囊保留根治性膀胱切除术（PSRC）是传统根治性膀胱切除术和新膀胱术的改良，为提高勃起功能和控尿功能的保留提供了前景。
方法
本文对这种方法治疗膀胱移行细胞癌的肿瘤学和生活质量结果进行了文献回顾，并将这些结果与传统的膀胱前列腺切除术和新膀胱术进行了比较。
结果
有少数研究涉及前列腺囊或前列腺保留性膀胱切除术。所有研究均为回顾性、非对照性的，且在患者选择和技术方面并不统一。缺乏长期随访。同期和/或异时性前列腺癌和前列腺尿道移行细胞癌的发生率低于传统膀胱前列腺切除术。这可能是由于术前患者选择，将该手术限制在没有任何疾病累及前列腺的患者。局部复发率为 5%，与标准膀胱前列腺切除术相当。无复发生存率和总生存率相当。
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