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巴拉那西部肾结石病的调查。

Investigation of nephrolithiasis in the West of Paraná.

作者信息

Peres Luis Alberto Batista, de Almeida Leandro Pelegrini, Bolson Luana Bertinato, Brites Mariana de Freitas, David Juliano Maximiano, Tazima Leandro

机构信息

Universidade Estadual do Oeste do Paraná.

出版信息

J Bras Nefrol. 2011 Apr-Jun;33(2):160-5.

Abstract

INTRODUCTION

Nephrolithiasis is com>mon and has a high rate of recurrence.

OBJECTIVES

To assess the prevalence of the main metabolic and anatomical changes and the chemical analysis of stone found in patients with nephrolithiasis in the West region of Paraná.

METHODS

Retrospective study with 681 adult patients with nephrolithiasis. The laboratory investigation included at least two samples of 24-hour urine test with doses of calcium, uric acid, citrate, oxalate, sodium and creatinine; qualitative cystinuria, urinary pH following 12-hour fast and water restriction, urine culture and chemical analysis, when the stones were available. Renal imaging techniques included at least renal ultrasound and excretory urogram.

RESULTS

The metabolic changes most frequently found were: hypercalciuria (51.8%), hyperuricosuria (27.6%), and hypocitraturia (23.5%). Chemical analysis of stones showed calcium oxa late in 85.7% of the cases. The most frequently anatomical changes were renal cyst, duplicated ureter, and ureteropelvic junction obstruction.

CONCLUSIONS

This paper served as a base for knowing the characteristics of patients with nephrolithiasis in the West area of Paraná.

摘要

引言

肾结石很常见,复发率高。

目的

评估巴拉那州西部地区肾结石患者主要代谢和解剖学变化的患病率以及结石的化学分析。

方法

对681例成年肾结石患者进行回顾性研究。实验室检查包括至少两份24小时尿液样本,检测钙、尿酸、柠檬酸盐、草酸盐、钠和肌酐的含量;定性胱氨酸尿症、禁食12小时并限制饮水后的尿液pH值、尿培养和化学分析(如有结石)。肾脏成像技术至少包括肾脏超声和排泄性尿路造影。

结果

最常见的代谢变化为:高钙尿症(51.8%)、高尿酸尿症(27.6%)和低枸橼酸盐尿症(23.5%)。结石的化学分析显示85.7%的病例为草酸钙结石。最常见的解剖学变化为肾囊肿、重复输尿管和输尿管肾盂连接处梗阻。

结论

本文为了解巴拉那州西部地区肾结石患者的特征提供了依据。

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