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新范式在预防心搏骤停和心力衰竭治疗中。

New paradigms in the prevention of sudden cardiac arrest and heart failure treatment.

机构信息

Division of Electrophysiology, Department of Cardiology, Tufts Medical Center, Boston, MA 02111, USA.

出版信息

Curr Cardiol Rep. 2011 Oct;13(5):377-86. doi: 10.1007/s11886-011-0204-3.

DOI:10.1007/s11886-011-0204-3
PMID:21789575
Abstract

Congestive heart failure is a very real public health issue not only in the United States, but worldwide. Mortality in patients with congestive heart failure is typically either sudden cardiac death or pump failure. Paradoxically, patients with less severe heart failure are at higher relative risk of sudden cardiac death. Defining which patients are best treated with implantable defibrillators and resynchronization is the purpose of this review.

摘要

充血性心力衰竭不仅是美国，也是全世界一个非常现实的公共卫生问题。充血性心力衰竭患者的死亡率通常是心源性猝死或泵衰竭。矛盾的是，心力衰竭程度较轻的患者发生心源性猝死的相对风险更高。本综述旨在确定哪些患者最适合使用植入式除颤器和再同步治疗。

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本文引用的文献

1
Left ventricular lead position and clinical outcome in the multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy (MADIT-CRT) trial.多中心自动除颤器植入试验-心脏再同步治疗（MADIT-CRT）试验中的左心室导线位置与临床结果。
Circulation. 2011 Mar 22;123(11):1159-66. doi: 10.1161/CIRCULATIONAHA.110.000646. Epub 2011 Mar 7.
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Meta-analysis: cardiac resynchronization therapy for patients with less symptomatic heart failure.荟萃分析：心脏再同步治疗症状较轻心力衰竭患者。
Ann Intern Med. 2011 Mar 15;154(6):401-12. doi: 10.7326/0003-4819-154-6-201103150-00313. Epub 2011 Feb 14.
3
Myocardial fibrosis predicts appropriate device therapy in patients with implantable cardioverter-defibrillators for primary prevention of sudden cardiac death.
心肌纤维化可预测植入式心脏复律除颤器治疗用于一级预防心源性猝死的患者中的适当设备治疗。
J Am Coll Cardiol. 2011 Feb 15;57(7):821-8. doi: 10.1016/j.jacc.2010.06.062.
4
Mortality rates and modes of death in heart failure patients with reduced versus preserved systolic function.射血分数降低与保留的心衰患者的死亡率和死亡模式。
Eur J Intern Med. 2011 Feb;22(1):53-6. doi: 10.1016/j.ejim.2010.10.004. Epub 2010 Nov 21.
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Non-evidence-based ICD implantations in the United States.美国基于非证据的 ICD 植入。
JAMA. 2011 Jan 5;305(1):43-9. doi: 10.1001/jama.2010.1915.
6
Relative merits of left ventricular dyssynchrony, left ventricular lead position, and myocardial scar to predict long-term survival of ischemic heart failure patients undergoing cardiac resynchronization therapy.左心室不同步、左心室导线位置和心肌瘢痕预测缺血性心力衰竭患者心脏再同步治疗长期生存的相对优势。
Circulation. 2011 Jan 4;123(1):70-8. doi: 10.1161/CIRCULATIONAHA.110.945345. Epub 2010 Dec 20.
7
Obesity paradox and risk of sudden death in heart failure results from the MUerte Subita en Insuficiencia cardiaca (MUSIC) study.肥胖悖论与心力衰竭猝死风险：来自 MUerte Subita en Insuficiencia cardiaca（MUSIC）研究的结果。
Am Heart J. 2011 Jan;161(1):158-64. doi: 10.1016/j.ahj.2010.10.018.
8
Heart disease and stroke statistics--2011 update: a report from the American Heart Association.心脏病和中风统计数据--2011 年更新：来自美国心脏协会的报告。
Circulation. 2011 Feb 1;123(4):e18-e209. doi: 10.1161/CIR.0b013e3182009701. Epub 2010 Dec 15.
9
Cardiac-resynchronization therapy for mild-to-moderate heart failure.心脏再同步治疗轻中度心力衰竭。
N Engl J Med. 2010 Dec 16;363(25):2385-95. doi: 10.1056/NEJMoa1009540. Epub 2010 Nov 14.
10
Eplerenone in patients with systolic heart failure and mild symptoms.依普利酮治疗有收缩性心力衰竭和轻度症状的患者。
N Engl J Med. 2011 Jan 6;364(1):11-21. doi: 10.1056/NEJMoa1009492. Epub 2010 Nov 14.