Liu Yun-zhi, Wang Wu-hong, Li Fang-cai, Yang Hao, Zhang Hong, Deng Zhi-hong, Wang Yuan, Chen Chang, Li Wen-chao, Zhang Heng-jiao, Liu Fu-qiang, Zhang Si-yu, Hu Shi-xiong
Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Feb;25(1):17-9.
To understand the infection condition and analytical methods of Influenza A (H1N1) virus in the population of Hunan Province during different periods.
Quick surveys on the positive rate of Influenza A (H1N1) virus hemagglutination inhibition (HI) test have been conducted for 5 times successively from November 2009 to March 2010 in 14 medical and health institutions of Changsha city, whose results were then compared with those from the sampling surveys of whole Hunan province.
2131 subjects were involved in this study; the total population standardized rates of antibody positive investigated for 5 times were 9.32% , 14.62%, 31.08%, 28.43% and 22.80% respectively; the population of 6-17-years-old has the highest rate of antibody positive; only 9.84% of the antibody positive subjects attributed to vaccine inoculation; there was no significant difference in the standardized positive rates between the quick serological surveys and the corresponding sampling survey of Hunan province (P > 0.05).
The positive rate of A (H1N1) virus antibody reached the peak in late January 2010; quick investigations in small region could be used to evaluate the infection prevalence during pandemic of infectious diseases.
了解湖南省不同时期人群甲型H1N1流感病毒的感染状况及分析方法。
2009年11月至2010年3月，在长沙市14家医疗卫生机构连续5次对甲型H1N1流感病毒血凝抑制（HI）试验阳性率进行快速调查，并与湖南省抽样调查结果进行比较。
本研究共纳入2131名受试者；5次调查的抗体阳性人群标准化总率分别为9.32%、14.62%、31.08%、28.43%和22.80%；6-17岁人群抗体阳性率最高；抗体阳性者中仅9.84%归因于疫苗接种；快速血清学调查与湖南省相应抽样调查的标准化阳性率无显著差异（P>0.05）。
甲型H1N1流感病毒抗体阳性率于2010年1月下旬达到高峰；小区域快速调查可用于评估传染病大流行期间的感染流行情况。
