Davis Melinda B, Duvernoy Claire S
Cardiology Section, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Womens Health (Lond). 2011 Jul;7(4):433-51. doi: 10.2217/whe.11.34.
More women die of cardiovascular disease than any other cause. Effective primary prevention depends on accurate assessment of risk status. While most risk factors are similar for men and women, risk factors may differ in magnitude between the sexes, and recognition of gender-specific risk factors such as gestational diabetes, hypertensive syndromes of pregnancy and polycystic ovarian syndrome provides opportunities for early intervention and prevention. Obesity, hypertension and hyperlipidemia affect both genders; however, women often postpone addressing these risk factors until later in life. The American Heart Association emphasizes that all women are at cardiovascular risk and should maintain a healthy lifestyle and avoid smoking. Blood pressure, hyperlipidemia and diabetes should be aggressively treated. Current available data regarding proposed preventive drug therapies including daily aspirin, HRT, vitamin D and omega-3 fatty acid supplements will be reviewed.
死于心血管疾病的女性比死于其他任何原因的女性都多。有效的一级预防取决于对风险状况的准确评估。虽然男性和女性的大多数风险因素相似,但两性之间风险因素的程度可能不同,识别妊娠糖尿病、妊娠高血压综合征和多囊卵巢综合征等特定性别的风险因素为早期干预和预防提供了机会。肥胖、高血压和高脂血症对两性都会产生影响;然而,女性往往会推迟处理这些风险因素,直到晚年。美国心脏协会强调,所有女性都有心血管疾病风险,应保持健康的生活方式并避免吸烟。应积极治疗高血压、高脂血症和糖尿病。将对目前有关包括每日服用阿司匹林、激素替代疗法、维生素D和ω-3脂肪酸补充剂在内的预防性药物疗法的现有数据进行综述。