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杆菌性血管瘤病:一种新确定的、假性肿瘤性、感染性皮肤血管疾病。

Bacillary angiomatosis: a newly characterized, pseudoneoplastic, infectious, cutaneous vascular disorder.

作者信息

Cockerell C J, LeBoit P E

机构信息

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas 75235-9072.

出版信息

J Am Acad Dermatol. 1990 Mar;22(3):501-12. doi: 10.1016/0190-9622(90)70071-o.

Abstract

Bacillary angiomatosis (also called epithelioid angiomatosis) is a newly recognized disease most often characterized by a cutaneous infection with reddish papules of vascular origin. It is caused by a weakly reactive gram-negative bacillus, which can be easily demonstrated in tissue sections with the Warthin-Starry stain. Bacillary angiomatosis usually responds readily to treatment with oral erythromycin, 250 to 500 mg, taken four times a day for 2 weeks to 1 month. Because the skin is the most common site of involvement, it is important that the dermatologist recognize this unusual condition. It is essential that treatment be started as soon as possible because deaths may result from visceral and mucosal involvement. The clinical, histologic, and microbiologic aspects of bacillary angiomatosis are discussed and depicted in detail and speculations regarding the pathogenesis are rendered.

摘要

杆菌性血管瘤病(也称为上皮样血管瘤病)是一种新发现的疾病,最常见的特征是由血管起源的红色丘疹引起的皮肤感染。它由一种弱反应性革兰氏阴性杆菌引起,这种杆菌在组织切片中用沃辛-斯塔里染色很容易显示出来。杆菌性血管瘤病通常对口服红霉素治疗反应良好,剂量为250至500毫克,每日服用4次,持续2周至1个月。由于皮肤是最常受累的部位,皮肤科医生认识到这种不寻常的情况很重要。必须尽快开始治疗,因为内脏和黏膜受累可能导致死亡。本文详细讨论并描述了杆菌性血管瘤病的临床、组织学和微生物学方面,并对其发病机制进行了推测。

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