Graftys SA, Eiffel Park, Bâtiment D, 415 Rue Claude Nicolas Ledoux, Pôle d'activités d'Aix en Provence, 13854 Aix en Provence CEDEX 3, France.
Inorg Chem. 2011 Sep 5;50(17):8252-60. doi: 10.1021/ic2007777. Epub 2011 Jul 27.
Addition of a gallium (Ga) precursor in the typical reaction protocols used for the preparation of β-tricalcium phosphate (β-TCP) led to novel Ga-doped β-TCP ceramics with rhombohedral structures (R3c space group). From the refinement of their X-ray diffraction patterns, it was found that the incorporation of Ga in the β-TCP network occurs by substitution of one of the five calcium (Ca) sites, while occupation of another Ca site decreases in inverse proportion to the Ga content in the structure. The Ga local environment and the modification of the phosphorus environments due to the Ga/Ca substitution in Ga-doped β-TCP compounds are probed using (31)P and (71)Ga magic-angle spinning NMR. A decrease of the unit cell volume is observed with increasing Ga content, together with improved mechanical properties. Indeed, the compressive strength of these new bioceramics is enhanced in direct proportion of the Ga content, up to a 2.6-fold increase as compared to pure β-TCP.
在用于制备β-磷酸三钙 (β-TCP) 的典型反应方案中添加镓 (Ga) 前体，导致具有菱面体结构 (R3c 空间群) 的新型 Ga 掺杂 β-TCP 陶瓷。通过对其 X 射线衍射图谱的精修，发现 Ga 在 β-TCP 网络中的掺入是通过取代五个钙 (Ca) 位之一发生的，而另一个 Ca 位的占据则与结构中的 Ga 含量成反比减少。使用 (31)P 和 (71)Ga 魔角旋转 NMR 探测 Ga 掺杂 β-TCP 化合物中 Ga/Ca 取代引起的 Ga 局部环境和磷环境的修饰。随着 Ga 含量的增加，观察到单位晶胞体积减小，同时机械性能得到改善。实际上，这些新型生物陶瓷的抗压强度与 Ga 含量成正比增加，与纯 β-TCP 相比，增加了 2.6 倍。
