Freire Mercedes, Rodríguez Jesús, Möller Ingrid, Valcárcel Antonio, Tornero Carmelo, Díaz Gemma, Armendáriz Yolanda, Paredes Silvia
Hospital Juan Canalejo, A Coruña, España.
Reumatol Clin. 2011 Jan-Feb;7(1):20-6. doi: 10.1016/j.reuma.2010.03.003. Epub 2010 Jun 15.
FUNDAMENTAL AND OBJECTIVE: Psychological impairment is frequent in patients with rheumatic diseases. The aim of the study was to assess the prevalence of symptoms of anxiety and depression in patients with psoriatic arthritis attending rheumatology clinics.
Multicentre cross-sectional study conducted in rheumatology clinics. Patients with psoriatic arthritis were recruited; variables retrieved were sociodemographic, clinical and patient centered (Hospital Anxiety and Depression scale o HADs, EQ-5D questionnaire, etc.). Prevalence in the study population was calculated as anxiety or depression symptoms by an HADs score ≥11 or those receiving pharmacological treatment. A logistics regression model was used to know which variables were related to symptoms of anxiety or depression.
A total of 495 patients were included, 42.8% were women and median (SD) age was 50.4 (12.7) years. Prevalence of symptoms of anxiety were 29.7% and prevalence of symptoms of depression was 17,6%. Patients with anxiety or depression symptoms had all EQ-5D dimensions affected (p<0.01). Higher prevalence of anxiety was related to being a woman, a mixed onset pattern with respect to peripheral joints and those treated with DMARD alone with respect to DMARD+NSAID or biologic alone. A higher depression prevalence was related to being a woman and a mixed onset pattern with respect to peripheral joints.
The prevalence of anxiety symptoms and the prevalence of depression symptoms are high among patients suffering psoriatic arthritis in the studied population.
基本情况与目的：心理障碍在风湿病患者中很常见。本研究的目的是评估在风湿科门诊就诊的银屑病关节炎患者中焦虑和抑郁症状的患病率。
在风湿科门诊进行的多中心横断面研究。招募银屑病关节炎患者；收集的变量包括社会人口统计学、临床和以患者为中心的变量（医院焦虑抑郁量表即HADS、EQ-5D问卷等）。通过HADS评分≥11或接受药物治疗来计算研究人群中焦虑或抑郁症状的患病率。使用逻辑回归模型来了解哪些变量与焦虑或抑郁症状相关。
共纳入495例患者，42.8%为女性，中位（标准差）年龄为50.4（12.7）岁。焦虑症状的患病率为29.7%，抑郁症状的患病率为17.6%。有焦虑或抑郁症状的患者所有EQ-5D维度均受影响（p<0.01）。焦虑患病率较高与女性、外周关节混合发病模式以及仅接受改善病情抗风湿药（DMARD）治疗而非DMARD+非甾体抗炎药（NSAID）或仅生物制剂治疗有关。抑郁患病率较高与女性和外周关节混合发病模式有关。
在所研究人群中，银屑病关节炎患者的焦虑症状患病率和抑郁症状患病率较高。
