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[Efficacy of adalimumab in Behçet's disease. Description of 6 cases].

作者信息

Calvo Catalá Javier, Campos Fernández Cristina, Rueda Cid Amalia, González-Cruz Cervellera María Isabel, Baixauli Rubio Aurelio, Pastor Cubillo María Dolores

机构信息

Servicio de Reumatología y Metabolismo Óseo, Consorcio Hospital General Universitario, Valencia, España. calvo

出版信息

Reumatol Clin. 2011 Jul-Aug;7(4):258-61. doi: 10.1016/j.reuma.2010.10.003. Epub 2011 Feb 18.

DOI:10.1016/j.reuma.2010.10.003
PMID:21794828
Abstract

Behçet's disease (BD) is a systemic vasculitis, with a more aggressive course in young males. Orogenital ulcers, uveitis and cutaneous lesions are the most frequent manifestations. We analyzed the effects of adalimumab on six patients with BD pretreated with inmunosupressive therapy, two of whom had received infliximab. We observed a good clinical response in all patients. To date, after a mean follow-up of 26.8 months, patients continue receiving adalimumab, with good clinical control, no adverse effects have been reported with adalimumab.

摘要

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2
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引用本文的文献

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Efficacy and safety of adalimumab in Behçet's disease-related uveitis: a multicenter retrospective observational study.阿达木单抗治疗白塞病相关性葡萄膜炎的疗效与安全性:一项多中心回顾性观察研究
Clin Rheumatol. 2017 Jan;36(1):183-189. doi: 10.1007/s10067-016-3480-x. Epub 2016 Nov 16.
2
Adalimumab in the management of Behçet's disease.阿达木单抗在白塞病治疗中的应用
Ther Clin Risk Manag. 2015 Apr 13;11:611-9. doi: 10.2147/TCRM.S56163. eCollection 2015.
3
Biologics in dermatology: an integrated review.皮肤科生物制剂:综合综述。
Indian J Dermatol. 2014 Sep;59(5):425-41. doi: 10.4103/0019-5154.139859.
4
Off-label uses of anti-TNF therapy in three frequent disorders: Behçet's disease, sarcoidosis, and noninfectious uveitis.抗 TNF 治疗在三种常见疾病中的超适应证应用:白塞病、结节病和非感染性葡萄膜炎。
Mediators Inflamm. 2013;2013:286857. doi: 10.1155/2013/286857. Epub 2013 Aug 1.