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从内照射剂量学角度对葡萄牙核医学实践的研究。

Study of nuclear medicine practices in Portugal from an internal dosimetry perspective.

作者信息

Bento J, Teles P, Neves M, Santos A I, Cardoso G, Barreto A, Alves F, Guerreiro C, Rodrigues A, Santos J A M, Capelo C, Parafita R, Martins B

机构信息

Instituto Tecnológico e Nuclear, Sacavém, Portugal.

出版信息

Radiat Prot Dosimetry. 2012 May;149(4):438-43. doi: 10.1093/rpd/ncr319. Epub 2011 Jul 26.

DOI:10.1093/rpd/ncr319
PMID:21795254
Abstract

Nuclear medicine practices involve the handling of a wide range of pharmaceuticals labelled with different radionuclides, for diagnostic and therapeutic purposes. This work intends to evaluate the potential risks of internal contamination of nuclear medicine staff in several Portuguese nuclear medicine services and to conclude about the requirement of a routine internal monitoring. A methodology proposed by the International Atomic Energy Agency (IAEA), providing a set of criteria to determine the need, or not, for an internal monitoring programme, was applied. The evaluation of the risk of internal contaminations in a given set of working conditions is based on the type and amount of radionuclides being handled, as well as the safety conditions with which they are manipulated. The application of the IAEA criteria showed that 73.1% of all the workers included in this study should be integrated in a routine monitoring programme for internal contaminations; more specifically, 100% of workers performing radioimmunoassay techniques should be monitored. This study suggests that a routine monitoring programme for internal exposures should be implemented in Portugal for most nuclear medicine workers.

摘要

核医学实践涉及处理大量标记有不同放射性核素的药物,用于诊断和治疗目的。这项工作旨在评估葡萄牙几家核医学服务机构中核医学工作人员内部污染的潜在风险,并就常规内部监测的必要性得出结论。应用了国际原子能机构(IAEA)提出的一种方法,该方法提供了一套标准来确定是否需要内部监测计划。在给定的一组工作条件下对内部污染风险的评估基于所处理的放射性核素的类型和数量,以及操作它们时的安全条件。IAEA标准的应用表明,本研究中所有工作人员的73.1%应纳入内部污染的常规监测计划;更具体地说,应监测100%执行放射免疫分析技术的工作人员。这项研究表明,葡萄牙应为大多数核医学工作人员实施内部照射的常规监测计划。

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PLoS One. 2018 Dec 19;13(12):e0209244. doi: 10.1371/journal.pone.0209244. eCollection 2018.
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