Stojnic J, Stefanovic A, Jeremic K, Kadija S, Jeftovic M, Jeremic J
Institute of Gynecology and Obstetrics, University of Belgrade, Clinical Centre of Serbia, Belgrade, Serbia.
Eur J Gynaecol Oncol. 2011;32(3):356-8.
Krukenberg tumors are mostly found as metastatic signet-ring cell adenomucinous carcinomas in young, premenopausal women. They are bilateral in 80% of the cases, and thus can be expected in pregnancy. A 31-year-old female was diagnosed by explorative laparotomy at 27 weeks of gestation with a Krukenberg tumor due to bilateral adnexal masses and a large amount of ascites. At surgery cesarean section with total abdominal hysterectomy, bilateral salpingo-oophorectomy, total omentectomy and pelvic lymphadenectomy was performed. The neonate died 24 hours later due to prematurity and respiratory distress syndrome. The primary site of the cancer was detected metachronously two months after surgery and postoperative chemotherapy, as stomach adenomucinous carcinoma. In spite of surgery and postoperative multiagent chemotherapy, the patient died six months from the diagnosis of Krukenberg.
库肯勃瘤多表现为年轻绝经前女性的转移性印戒细胞腺黏液癌。80%的病例为双侧性,因此在妊娠时也可能出现。一名31岁女性在妊娠27周时因双侧附件肿块和大量腹水,经剖腹探查诊断为库肯勃瘤。手术行剖宫产加全腹子宫切除术、双侧输卵管卵巢切除术、全大网膜切除术和盆腔淋巴结清扫术。新生儿24小时后因早产和呼吸窘迫综合征死亡。癌症的原发部位在手术后两个月及术后化疗后被同步发现,为胃腺黏液癌。尽管进行了手术和术后多药化疗,患者在诊断为库肯勃瘤后6个月死亡。