Koenders P G, Pieters G F, Beex L V, Smals A G, Vooys G P, Kloppenborg P W
Sint-Radboudziekenhuis, Nijmegen, afd. Endocriene ziekten.
Ned Tijdschr Geneeskd. 1990 Mar 10;134(10):486-90.
In retrospect we analysed 175 fine needle aspiration biopsies, performed on 154 patients with a palpable, solitary, 'cold', thyroid nodule. In contrast to conventional diagnostic methods such as ultrasound and scintigraphy fine needle aspiration is a highly specific method for the detection of thyroid cancer. We found a significant difference in the frequency of thyroid carcinoma between patients operated because of cytological diagnosis and patients operated because of clinical suspicion of cancer, 44% and 20% respectively. We conclude that fine needle aspiration is a major step forward in the evaluation of solitary thyroid nodules.
回顾性分析了154例可触及的孤立性“冷”甲状腺结节患者的175次细针穿刺活检。与超声和闪烁扫描等传统诊断方法不同，细针穿刺是检测甲状腺癌的高度特异性方法。我们发现，因细胞学诊断而接受手术的患者与因临床怀疑癌症而接受手术的患者相比，甲状腺癌的发生率存在显著差异，分别为44%和20%。我们得出结论，细针穿刺是评估孤立性甲状腺结节的一项重大进展。
