Wolf H, Leschot N J, van den Kroonenberg M T, Walford N, Lammes F B
Afd. Verloskunde en Gynaecologie, Academisch Medisch Centrum, Amsterdam.
Ned Tijdschr Geneeskd. 1990 Feb 24;134(8):394-7.
In two pregnant women the diagnosis fetal triploidy was made by transabdominal villous biopsy at 20 and 21 weeks. Chromosomal analysis revealed a 69, XXX respectively 69, XXY karyotype. The diagnosis was suspected because of fetal growth retardation and a large vesicular placenta on sonographic examination. One patient had bilateral multilocular ovarian cysts. She had an eclamptic seizure at 22 weeks. In both patients labour was induced by intravenous prostaglandins. One fetus had a small spina bifida, the other fetus had no congenital malformations. Microscopy of both placentas showed a partial mole. A short description is given of the abnormalities associated with triploidy.
在两名孕妇中，经腹绒毛活检于孕20周和21周时确诊为胎儿三倍体。染色体分析显示核型分别为69, XXX和69, XXY。超声检查因胎儿生长受限和巨大水泡状胎盘而怀疑该诊断。一名患者有双侧多房性卵巢囊肿。她在孕22周时发生子痫发作。两名患者均通过静脉注射前列腺素引产。一个胎儿有小的脊柱裂，另一个胎儿无先天性畸形。两个胎盘的显微镜检查均显示部分性葡萄胎。本文对与三倍体相关的异常情况进行了简要描述。
