Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Semin Perinatol. 2011 Aug;35(4):234-9. doi: 10.1053/j.semperi.2011.02.020.
In the United States, there is a pronounced and persistent race/ethnic disparity in the rate of preterm birth. Even after decades of basic science research and public health initiatives this disparity remains relatively unchanged. Factors that underpin this disparity are elusive and likely, at least in part, derived from complex mechanisms originating from social inequities. In this article several promising areas of research are explored. Specifically, social context or neighborhood-level exposures, maternal nativity, infection/inflammation, and preconception health differentials are discussed in the context of increasing risk of preterm birth among race/ethnic minorities.
在美国,早产率存在明显且持久的种族/民族差异。尽管经过几十年的基础科学研究和公共卫生措施,这种差异仍然相对不变。造成这种差异的因素难以捉摸,而且可能至少部分源于源自社会不平等的复杂机制。本文探讨了几个有前途的研究领域。具体来说,在种族/少数民族早产风险增加的背景下,讨论了社会环境或邻里水平暴露、产妇原籍国、感染/炎症和孕前健康差异等问题。