角化成釉细胞瘤：成釉细胞瘤的复杂组织学变异型。
Keratoameloblastoma: complex histologic variant of ameloblastoma.
作者信息
Sisto John M, Olsen Gregory G
机构信息
Department of Oral and Maxillofacial Surgery, Cook County Hospital, Chicago, IL, USA.
出版信息
J Oral Maxillofac Surg. 2012 Apr;70(4):860-4. doi: 10.1016/j.joms.2011.03.033. Epub 2011 Jul 27.
Keratoameloblastoma is a rare subtype of ameloblastoma that has been reported only 12 times previously in the literature. Ameloblastomas are benign, locally aggressive neoplasms that constitute approximately 1% of odontogenic neoplasms. The mandible is involved in 80% of cases and the maxilla 20%. Clinically, these appear as solid, unicystic, multicystic, and mixed solid and multicystic tumors. Histologically, these are classified as follicular, plexiform, acanthomatous, and granular cell. Less common histologic variants are clear cell, desmoplastic, basal cell, papilliferous, and keratoameloblastoma. This report presents a new case to the literature, reviews histologic findings and radiographic appearance, and discusses the clinical significance of this tumor with respect to treatment based on currently available literature.
角化成釉细胞瘤是成釉细胞瘤的一种罕见亚型，此前文献中仅报道过12例。成釉细胞瘤是良性、局部侵袭性肿瘤，约占牙源性肿瘤的1%。80%的病例累及下颌骨，20%累及上颌骨。临床上，这些肿瘤表现为实性、单囊性、多囊性以及实性和多囊性混合的肿瘤。组织学上，它们被分类为滤泡型、丛状型、棘皮瘤型和颗粒细胞型。不太常见的组织学变异型有透明细胞型、促结缔组织增生型、基底细胞型、乳头状型和角化成釉细胞瘤。本报告向文献中呈现了一例新病例，回顾了组织学 findings 和影像学表现，并根据现有文献讨论了该肿瘤在治疗方面的临床意义。
需注意，原文中“findings”未翻译完整，应补充完整其确切含义，比如“发现”“表现”等，可根据上下文灵活调整。整体译文可优化为：
角化成釉细胞瘤是成釉细胞瘤的一种罕见亚型，此前文献中仅报道过12例。成釉细胞瘤是良性、局部侵袭性肿瘤，约占牙源性肿瘤的1%。80%的病例累及下颌骨，20%累及上颌骨。临床上，这些肿瘤表现为实性、单囊性、多囊性以及实性和多囊性混合的肿瘤。组织学上，它们被分类为滤泡型、丛状型、棘皮瘤型和颗粒细胞型。不太常见的组织学变异型有透明细胞型、促结缔组织增生型、基底细胞型、乳头状型和角化成釉细胞瘤。本报告向文献中呈现了一例新病例，回顾了组织学表现和影像学表现，并根据现有文献讨论了该肿瘤在治疗方面的临床意义。
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