Physiotherapy Department, College of Medicine, University of Ibadan, Nigeria.
Physiother Theory Pract. 2012 Jan;28(1):32-40. doi: 10.3109/09593985.2011.570858. Epub 2011 Jul 31.
Disability resulting from knee osteoarthritis (OA) is determined by physiological and functional variables though the interactions between the variables remain unclear and deserve further study. This study's major objective was to explore the relationship between pain, body mass index (BMI), balance, self-report function, and physical function in a cohort who had both unilateral and bilateral knee OA. Fifty-two patients (46 female, 6 male) ranging from 31 to 80 years of age (mean ± SD: 59.0 ± 9.8 years) with radiograph-confirmed OA of the knees participated in this study. Participants' pain intensity, self-reported function, dynamic balance, and physical function performance were measured by using box numerical scale, OA Index of Lequesne, functional reach test, and both stair climbing and timed up-and-go (TUG) tests, respectively. Associations between age, BMI, pain, balance, self-reported function, and physical function performance were explored by univariate and multivariate analyses at α = 0.05. Significant direct correlations were found between physical function performance and self-reported function (r = 0.56, r = 0.01) and age (r = 0.55, p = 0.01) and between self-reported function and age (r = 0.40, p = 0.01) in the cohort with bilateral knee OA. Significant inverse correlation was observed between age and balance (r = -0.58, p = 0.01) in participants with unilateral knee OA. In the regression model for all participants, self-reported function and age accounted for 27.0% of the variance in stair climbing test and 29.0% of the variance in the TUG test. Self-reported function and age are significant predictors of physical function in individuals with knee OA.
膝关节骨关节炎（OA）导致的残疾取决于生理和功能变量，但这些变量之间的相互作用尚不清楚，值得进一步研究。本研究的主要目的是探讨在单侧和双侧膝关节 OA 患者队列中，疼痛、体重指数（BMI）、平衡、自我报告功能和身体功能之间的关系。52 名患者（46 名女性，6 名男性）年龄 31 至 80 岁（平均±标准差：59.0±9.8 岁），膝关节放射照相证实有 OA。使用箱式数字量表、OA 膝关节 Lequesne 指数、功能性伸展试验以及上下楼梯和计时起立行走（TUG）试验分别测量了参与者的疼痛强度、自我报告功能、动态平衡和身体功能表现。通过单变量和多变量分析，在α=0.05 的水平上探讨了年龄、BMI、疼痛、平衡、自我报告功能和身体功能表现之间的相关性。在双侧膝关节 OA 队列中，身体功能表现与自我报告功能（r=0.56，r=0.01）和年龄（r=0.55，p=0.01）之间以及自我报告功能与年龄（r=0.40，p=0.01）之间存在显著的直接相关性。在单侧膝关节 OA 患者中，观察到年龄与平衡之间存在显著的负相关（r=-0.58，p=0.01）。在所有参与者的回归模型中，自我报告功能和年龄解释了上下楼梯试验中 27.0%的变异性和 TUG 试验中 29.0%的变异性。自我报告功能和年龄是膝关节 OA 患者身体功能的重要预测因素。
