Caralis P V
Department of Medicine, University of Miami School of Medicine, Florida.
Am J Med. 1990 Mar 12;88(3B):9S-16S. doi: 10.1016/0002-9343(90)90004-w.
According to the 1988 census, there are 19.4 million Hispanics living in the United States. They represent 8.1 percent of the nation's population, and that percentage is expected to rise significantly in the next 25 years. Demographic projections indicate that Hispanics will become the largest minority group in the United States by the year 2000, yet they remain a seriously understudied population. This article examines available clinical data, epidemiologic findings, and sociologic observations regarding the incidence of hypertension in this minority group and summarizes what is known about the detection, evaluation, treatment, and control of high blood pressure in Hispanics. In addition, the preliminary results of a multi-center, placebo-controlled trial comparing the efficacy and safety of a potassium-sparing diuretic (Dyazide; Smith Kline & French Laboratories) in Hispanic-American patients with mild-to-moderate hypertension are presented.
根据1988年的人口普查，有1940万西班牙裔人生活在美国。他们占美国人口的8.1%，预计在未来25年这一比例将大幅上升。人口预测表明，到2000年西班牙裔人将成为美国最大的少数族裔群体，但他们仍然是一个研究严重不足的人群。本文研究了关于这个少数族裔群体高血压发病率的现有临床数据、流行病学发现和社会学观察结果，并总结了关于西班牙裔人高血压的检测、评估、治疗和控制方面已知的情况。此外，还介绍了一项多中心、安慰剂对照试验的初步结果，该试验比较了一种保钾利尿剂（Dyazide；史克必成实验室）在患有轻度至中度高血压的美籍西班牙裔患者中的疗效和安全性。
