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多学科血管异常诊所中婴儿血管瘤的外科治疗

Surgical treatment of infantile hemangioma in a multidisciplinary vascular anomalies clinic.

作者信息

Daramola Opeyemi O, Chun Robert H, Nash John J, Drolet Beth A, North Paula E, Jensen John N, Kerschner Joseph E

机构信息

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin and Affiliated Hospitals, Milwaukee, WI, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2011 Oct;75(10):1271-4. doi: 10.1016/j.ijporl.2011.07.007. Epub 2011 Jul 30.

Abstract

OBJECTIVE

(1) Discuss indications for surgical treatment of infantile hemangioma (IH); (2) describe outcomes, management of complications and long term surveillance of surgically treated IH.

STUDY DESIGN

Retrospective.

SUBJECTS AND METHODS

The charts of children seen in a dedicated vascular anomalies center at a tertiary pediatric hospital were reviewed.

RESULTS

Out of 1012 patients diagnosed with IH over 27 months, 92 patients, predominantly caucasian female, with an average age of 36 months, underwent surgery for 94 lesions. Head and neck lesions accounted for 67% of the population and 51 lesions were located on the face. Surgical indications included bleeding, functional impairment, ulceration and cosmetic disfigurement. Mean surface area was 7.75 cm². Although lesions requiring additional procedures were larger (median 5.5 cm²) than single-stage excisions, this difference was not statistically significant (P=0.09). Head and neck lesions were more likely to require multiple modality treatment (P=0.003). There was no identified objective criteria to predict head and neck lesions that are more likely to be associated post-operative complications.

CONCLUSIONS

Most IH do not require treatment. The majority of infantile hemangioma occurred on the head and neck. When significant functional impairment, ulceration, bleeding, cosmetic deformity is encountered or anticipated, surgical therapy can be performed at any clinical phase with few complications and favorable outcomes.

摘要

目的

(1)探讨婴儿血管瘤(IH)的手术治疗指征;(2)描述手术治疗IH的结果、并发症处理及长期监测情况。

研究设计

回顾性研究。

研究对象与方法

回顾一家三级儿童医院专门的血管异常中心诊治的儿童病历。

结果

在27个月内确诊为IH的1012例患者中,92例(主要为白种女性,平均年龄36个月)因94处病损接受了手术。头颈部病损占67%,51处位于面部。手术指征包括出血、功能障碍、溃疡及美容缺陷。平均表面积为7.75平方厘米。尽管需要额外手术的病损比一期切除的病损更大(中位数为5.5平方厘米),但差异无统计学意义(P = 0.09)。头颈部病损更可能需要多种治疗方式(P = 0.003)。未发现可预测头颈部病损更易发生术后并发症的客观标准。

结论

大多数IH无需治疗。大多数婴儿血管瘤发生于头颈部。当出现或预期有明显功能障碍、溃疡、出血、美容畸形时,手术治疗可在任何临床阶段进行,并发症少且预后良好。

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