Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
J Vasc Surg. 2011 Nov;54(5):1290-1297.e2. doi: 10.1016/j.jvs.2011.05.045. Epub 2011 Jul 31.
Incidental abdominal aortic aneurysms (AAAs) are identified when the abdomen is imaged for other reasons. These are common, and many undergo incomplete radiological monitoring. The association between monitoring completeness and population-based outcomes has not been studied.
A cohort of incidental AAAs (defined as previously unidentified aortic enlargement exceeding 3 cm found on an imaging study done for another reason) was linked to population-based data. Patients were followed to elective AAA repair, AAA rupture, death, or March 31, 2009. Monitoring completeness was gauged as the sequential number of months without a recommended abdominal scan. Its association with time to elective AAA repair and time to death was measured using a multivariable Cox regression model adjusting for other important covariates.
We identified 191 incidental AAAs between 1996 and 2004 (median diameter of 3.5 cm [range, 3.0-5.3 cm], median follow up of 4.4 years [range, 0.6-12.7 years]). During the study, patients spent a median of 19.4% of their time with incomplete AAA monitoring (interquartile range [IQR] 0.3%-44%); 56 patients (29.3%) had no follow-up imaging of their aneurysm. Nineteen patients (10.0%; 2.0% per year) underwent elective AAA repair, and 79 patients (37.7%; 7.6% per year) died. Independent of important covariates, people were significantly less likely to undergo elective repair (hazard ratio [HR], 0.03) and significantly more likely to die (HR, 2.99) if their AAA went without radiological monitoring for 1 year.
Incomplete incidental AAA radiological monitoring was significantly associated with a decreased risk of elective AAA repair and an increased risk of death. While uncontrolled confounding might explain part of these associations, clinicians should ensure that radiological monitoring of AAAs is complete in appropriate patients.
当腹部因其他原因进行成像检查时,会发现偶然的腹主动脉瘤(AAA)。这些是常见的,许多人接受不完全的影像学监测。监测完整性与基于人群的结果之间的关联尚未得到研究。
一组偶然的 AAA 患者(定义为在因其他原因进行的影像学研究中发现的先前未识别的主动脉扩张超过 3cm)与基于人群的数据相关联。患者随访至择期 AAA 修复、AAA 破裂、死亡或 2009 年 3 月 31 日。监测完整性的评估标准是连续无推荐腹部扫描的月数。使用多变量 Cox 回归模型,根据其他重要协变量调整,测量其与择期 AAA 修复时间和死亡时间的相关性。
我们在 1996 年至 2004 年间发现了 191 例偶然的 AAA(中位直径 3.5cm[范围,3.0-5.3cm],中位随访时间 4.4 年[范围,0.6-12.7 年])。在研究期间,患者有中位 19.4%的时间存在不完全的 AAA 监测(四分位间距[IQR]0.3%-44%);56 例患者(29.3%)没有对其动脉瘤进行后续成像。19 例患者(10.0%;每年 2.0%)接受了择期 AAA 修复,79 例患者(37.7%;每年 7.6%)死亡。独立于重要协变量,与 AAA 未进行影像学监测 1 年相比,患者接受择期修复的可能性显著降低(风险比[HR],0.03),死亡的可能性显著增加(HR,2.99)。
不完全的偶然 AAA 影像学监测与择期 AAA 修复风险降低和死亡风险增加显著相关。虽然未控制的混杂因素可能部分解释了这些关联,但临床医生应确保适当患者的 AAA 影像学监测完整。