5-烷氧基甲基尿嘧啶类似物的合成、反应性和生物活性。
Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues.
机构信息
Department of Organic Chemistry, Faculty of Science, Institute of Molecular and Translational Medicine, Palacky University, 17. Listopadu 12, 771 46 Olomouc, Czech Republic. Tel.: +420 585 634 405;
出版信息
Beilstein J Org Chem. 2011;7:678-98. doi: 10.3762/bjoc.7.80. Epub 2011 May 26.
This review article summarizes the results of a long-term investigation of 5-alkoxymethyluracil analogues and is aimed, in particular, at methods of syntheses. Most of the presented compounds were synthesized in order to evaluate their biological activity, therefore, a brief survey of biological activity, especially antiviral, cytotoxic and antibacterial, is also reported.
这篇综述文章总结了对 5-烷氧基甲基尿嘧啶类似物的长期研究结果，特别是针对合成方法。为了评估它们的生物活性，本文介绍了大多数所呈现的化合物的合成方法，因此，也报告了它们的生物活性，特别是抗病毒、细胞毒性和抗菌活性的简要调查。
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