Willig Amanda L, Hanks Lynae J, Fernandez Jose R
Department of Nutrition Sciences and the Clinical Nutrition Research Center.
Open Obes J. 2011 Mar 1;3:4-8. doi: 10.2174/1876823701103010004.
Several studies have indicated that birth weight is associated with increased risk for excess fat accumulation later in life. Our objective was to evaluate the association between birth weight and body composition measures in a multiethnic pediatric population while controlling for environmental factors previously associated with increased adiposity. Dual-energy x-ray absorptiometry was performed on 256 European-American, African-American, and Hispanic-American boys and girls. Body composition measurements were adjusted by height to create a fat mass index, fat-free mass index, and trunk fat mass index. After adjusting for age, pubertal status, sex, race/ethnicity, socioeconomic status, and physical activity, we found that higher birth weights were associated with significant increases in all three body composition indices (P < 0.05). After adjusting for physical activity in analysis of covariance, the relationship between birth weight and the fat-free mass index was no longer significant. This study suggests that higher birth weight is a risk factor for later unfavorable body composition changes in children, and that current environment and physical activity habits can affect these outcomes.
多项研究表明，出生体重与日后生活中脂肪过度积累的风险增加有关。我们的目标是在一个多民族儿科人群中评估出生体重与身体成分测量值之间的关联，同时控制先前与肥胖增加相关的环境因素。对256名欧美、非裔美国和西班牙裔美国男孩和女孩进行了双能X线吸收法测量。身体成分测量值根据身高进行调整，以创建脂肪量指数、去脂体重指数和躯干脂肪量指数。在调整了年龄、青春期状态、性别、种族/民族、社会经济地位和身体活动后，我们发现较高的出生体重与所有三个身体成分指数的显著增加有关（P<0.05）。在协方差分析中调整身体活动后，出生体重与去脂体重指数之间的关系不再显著。这项研究表明，较高的出生体重是儿童日后身体成分发生不利变化的一个危险因素，并且当前的环境和身体活动习惯会影响这些结果。
