Tianjin Women and Children's Health Center, Tianjin, China.
Prev Med. 2009 Aug-Sep;49(2-3):172-8. doi: 10.1016/j.ypmed.2009.07.013. Epub 2009 Jul 24.
To investigate the association between different levels of birth weight and the risk of overweight and obesity in children aged 3-6 years.
A retrospective longitudinal study of 15,852 children aged 3-6 years in Tianjin, China. Body weight and height, and other factors (age, gestational age, past and current health status, father's and mother's education, occupation and health status, family income, and sex) were obtained using standardized methods.
After adjustment for the above other factors, Chinese children who were born with a birth weight below 2500 g are less likely to become overweight or obese (body mass index more than the 85th percentiles for age and gender specific distribution using the World Health Organization growth reference) during childhood (odd ratio [OR] 0.84, 95% confidence interval [CI] 0.47-1.52) when compared to the reference group (2500-2999 g). However, the odds ratios of becoming overweight or obese during childhood increase significantly when birth weights are 3000-3499 g (OR 1.58, 95% CI 1.33-1.88), 3500-3999 g (OR 2.09, 95% CI 1.76-2.49), and more than 4000 g (OR 3.14, 95% CI 2.60-3.79).
High levels of birth weight, defined as birth weight >3000 g, were a stronger predictor for overweight and obesity among the Chinese children aged 3-6 years.
探讨不同出生体重水平与 3-6 岁儿童超重和肥胖风险的关系。
在中国天津进行了一项回顾性纵向研究，共纳入 15852 名 3-6 岁儿童。采用标准化方法测量儿童的体重、身高和其他因素（年龄、胎龄、既往和当前健康状况、父母的教育程度、职业和健康状况、家庭收入和性别）。
在调整了上述其他因素后，与参考组（2500-2999g）相比，出生体重低于 2500g 的中国儿童在儿童期更不容易超重或肥胖（体重指数超过年龄和性别特定分布的第 85 百分位数，采用世界卫生组织生长参考）（比值比 [OR]0.84，95%置信区间 [CI]0.47-1.52）。然而，当出生体重为 3000-3499g（OR1.58，95%CI1.33-1.88）、3500-3999g（OR2.09，95%CI1.76-2.49）和超过 4000g（OR3.14，95%CI2.60-3.79）时，儿童期超重或肥胖的几率比显著增加。
高出生体重（定义为出生体重>3000g）是中国 3-6 岁儿童超重和肥胖的更强预测指标。
